Assuming your instance has it, use the “block” feature on communities. I like to browse the “all” version of lemmy.world; but ya, it’s a lot of memes and stuff I don’t care to engage with. So, I’ll open a new tab to that community and hit the “block community” button. That community no longer shows up.

You can also block specific users. I use this on a lot of the re-post bots. Similar procedure, open the user’s profile and “Block User”.

It makes browsing “all” far more enjoyable.