Let’s say we left one single very smart guy (not necessarily with the knowledge: they may be able to understand hard stuff when taught it, but not know it already) alone on a copy of the earth. That person is also immortal. Could that person, by themselves, gain back all knowledge, maybe also experimental, or even surpass that is already available to us right now, before the planet gets inevitably engulfed by a sun turning red giant?
Probably not if you subscribe to https://en.m.wikipedia.org/wiki/Planck's_principle
given enough time, the lone scientist may display something similar to change between generations maybe